Home Print this page Email this page
Users Online: 204
Year : 2019  |  Volume : 11  |  Issue : 1  |  Page : 14-18

Dry eye disease and tear dysfunction in patients with type 2 diabetes: A hospital-based study from South India

Department of Ophthalmology, PSG Institute of Medical Sciences and Research, Coimbatore, Tamil Nadu, India

Correspondence Address:
Dr K Divya
Associate Professor, Department of Ophthalmology, PSG Institute of Medical Sciences and Research, Coimbatore - 641 004, Tamil Nadu
Login to access the Email id

DOI: 10.4103/sjopthal.sjopthal_4_19

Rights and Permissions

Purpose: Diabetics are more prone to dry eye disease (DED) and tear film dysfunction. The aim of this study was to assess the frequency of DED and tear film abnormalities in patients with type 2 diabetes compared to healthy controls. Materials and Methods: This was a hospital-based prospective case-control study. One hundred patients with type 2 diabetes and 100 healthy controls were enrolled by consecutive sampling. All study participants completed the Ocular Surface Disease Index (OSDI) questionnaire to score dry eye symptoms. Tear film breakup time (TFBUT), ocular surface staining with fluorescein and Schirmer's test were performed, and results were analyzed. Student's t-test was applied for comparisons between groups. Correlation between variables was detected using Pearson's correlation coefficient. Statistical significance was set at P < 0.05. Results: Dry eye was encountered in 54 among the 100 diabetic patients studied. Age and sex of diabetic patients were not found to affect the dry eye status. Longer duration of diabetes was significantly associated with DED (P = 0.03). Significant differences in OSDI scores, TFBUT, fluorescein staining, and Schirmer's test values were observed between the study groups (P < 0.001). An increased level of glycosylated hemoglobin was significantly associated with abnormal tear function tests. Conclusion: Patients with longer duration of diabetes and poor glycemic control are more predisposed to have abnormalities of the tear film and DED. Apart from conventional therapies, optimal glycemic control should be an important consideration in the management of tear dysfunction in diabetic patients.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded344    
    Comments [Add]    

Recommend this journal